The study investigates the impact of moderate-intensity swimming on oxidative injury in ischemic hearts, using male rats divided into three groups: pre-swimming training + isoproterenol (ISO) treated, isoproterenol-treated, and control-sedentary. Results show that swimming significantly reduces cardiac injury biomarkers (ANP, BNP) and reactive oxygen species (ROS) levels, while increasing antioxidant enzymes (CAT, SOD, GPx) in the heart. The findings suggest that moderate-intensity swimming can effectively prevent myocardial infarction-induced ischemic injury by inhibiting ROS production and enhancing intracellular antioxidant defense.

The study investigates the degradation patterns of engine oils in diesel and petrol engines using mass spectrometry. It highlights the faster degradation of petrol engine oils, especially under short-range utilization, due to higher oxidation and nitration. The research provides detailed insights into the chemical processes affecting antioxidants, antiwear additives, and detergents, emphasizing the need for advanced oil formulations to withstand alternative fuels. The findings are crucial for understanding oil-fuel interactions and optimizing engine oils for prolonged service life and sustainability.

Comprehensive guide to the design and construction of process equipment and storage tanks, covering theoretical fundamentals, calculation methods, dimensioning techniques, and finite element examination results. Highlights corrosion-proof design through real-world examples, with all results based on original research.

Electrochemotherapy (ECT) has significantly evolved, expanding treatment indications from superficial skin lesions to advanced-stage, deep-seated tumors. Technological improvements in electrodes, including the introduction of laparoscopic electrodes, have made minimally invasive ECT a reality. The role of ECT in oncology is still being determined, but its increased tumor response, pain relief, and low adverse events suggest potential for wider application and inclusion in international guidelines. This review provides an overview of the current status of ECT in deep-seated tumor treatment and its emerging role in local anticancer therapy.

The study establishes the conditions necessary for the maintenance and differentiation of human cortical neuroepithelial stem cells (cNESCs) derived from human pluripotent stem cells (hPSCs). By using a combination of six factors (FGF, BMPRi, TGFβRi, GSK3i, AKTi, and TNKS), termed 6F, the researchers were able to support the self-renewal and proliferation of cNESCs while preserving their cortical marker expression and differentiation potential. The cNESCs maintained their ability to differentiate into various cortical neurons and glial cells, both in vitro and in vivo, following the embryonic developmental order. The findings highlight the importance of regulating specific signaling pathways to maintain the neuroepithelial state and potential of cNESCs, providing insights into cortical development and potential applications in regenerative medicine.

The Hungarian speed skating team is preparing for the Beijing Winter Olympics with high hopes for winning medals despite the challenges posed by the pandemic. The team has adopted strict quarantine measures to ensure safety. Key members include brothers Sandor Shaolin Liu and Shaoang Liu, who have a mixed Chinese-Hungarian heritage. The team's preparation is bolstered by the expertise of Chinese coach Lina Zhang, who has integrated Asian training methods with Western practices. Coach Akos Banhidi emphasizes the importance of hard work and the unpredictable nature of the sport.

Starting from January 3, 2022, unvaccinated school teachers in Hungary who have not received their COVID-19 vaccination by December 30, 2021, are being put on unpaid leave. They can only return to work with a negative PCR test, which they must pay for themselves. The Democratic Trade Union of Teachers criticizes the decision for not being comprehensive and for potentially causing a shortage of educators. In contrast, a private school has given teachers the choice to vaccinate, a decision that one teacher believes is wise.

China's National Youth Orchestra performed in Budapest for the first time in two years, marking a significant cultural exchange between China and Hungary. Despite travel restrictions affecting some musicians, the concert was a success, featuring works by Liszt, Bartok, Rossini, and contemporary Chinese composers. The event, seen as a prelude to the Winter Olympics in Beijing, was praised for its collaborative spirit and sold out all 260 seats. Organizers and performers expressed excitement and hope for future full-orchestra performances.

Budapest's Vörösmarty Square Christmas market requires visitors to present a vaccination card or immunity certificate due to pandemic safety measures. The director of the organizing Budapest agency, Csaba Faix, explained that this measure ensures visitor safety and complies with Hungarian law for events exceeding 500 people. Despite some traders' concerns about reduced participation, the market features nearly 50 artisan stalls and introduces cash-free payment options for the first time.

The Hungarian Competition Authority (HCA) has launched a market study to examine the data collection practices of online retailers, the purposes for which this data is used, and consumer awareness and opinions on these practices. The study also aims to understand the competitive advantages conferred by data and the barriers to entry these practices create, particularly for Hungarian SMEs. The HCA, which has both competition enforcement and consumer protection roles, initiated this study due to the increasing popularity of online retail during the pandemic. The study focuses on technology, clothing, and food-retail sectors.

The European Commission's proposed Digital Markets Act (DMA) aims to ensure fair and competitive conditions for businesses and consumers by regulating large systemic online platforms, known as gatekeepers. The DMA sets obligations for gatekeepers, including interoperability with third-party services, data access for businesses, and restrictions on self-preferencing. The European Commission, supported by the Digital Markets Advisory Committee, will enforce these obligations and can impose fines up to 10% of net turnover.

The Digital Markets Act (DMA) proposal by the European Commission (EC) aims to regulate large digital service providers, termed 'gatekeepers,' to ensure fair competition and consumer welfare. The DMA outlines criteria for identifying gatekeepers and grants the EC and Member States the authority to designate such entities. The act focuses on core platform services and includes both qualitative criteria and presumption thresholds for gatekeeper designation. The DMA also addresses the relationship between EU-level and local laws, emphasizing the need for a unified regulatory approach to avoid fragmentation. The act is expected to impact both global and local digital service providers in the EU and CEE regions, imposing new obligations to maintain a fair digital market.

The European Commission has proposed two legislative acts, the Digital Services Act (DSA) and the Digital Markets Act (DMA), to manage digitalisation within the EU. These acts aim to create a fair, innovative, and competitive digital environment by regulating digital services and gatekeeper entities. The DMA, in particular, targets large online platforms to ensure fair competition and prevent unfair practices. The proposals will undergo the EU legislative process, with potential adoption taking over a year. The DMA is expected to significantly impact businesses and consumers by establishing a clear legal framework for digital markets.

The Hungarian Competition Authority (HCA) has launched an investigation into TikTok, focusing on consumer protection issues related to data collection and user information. The HCA's digital consumer protection strategy has previously led to significant actions against companies like Google and Academic Singles for similar issues. The authority aims to ensure transparency and protect consumers in the rapidly evolving digital market, with ongoing investigations into other platforms like Viber.

Researchers developed a protocol to differentiate mouse embryonic stem cells into renal progenitors in vitro, bypassing the use of embryoid bodies and using a monolayer culture method. This approach aims to mimic embryonic kidney development and could be valuable for therapeutic applications and regenerative medicine. The study also explored the effects of gene over-expression on kidney differentiation, finding that over-expression inhibited differentiation, suggesting precise gene regulation is critical for development. The work was conducted at the Lunenfeld Tanenbaum Research Institute at Mount Sinai Hospital in Toronto, Canada.

Opera legend Placido Domingo performed at a concert in Szeged, Hungary, to inaugurate a sports and youth complex despite facing sexual harassment allegations. The allegations, reported by The Associated Press, span decades and involve claims of Domingo pressuring women into sexual relationships under professional pretexts. Domingo has denied the allegations, considering his interactions consensual. The concert also featured performances by Placido Domingo Jr., Ana Maria Martinez, and others. The sports complex, owned by the Roman Catholic diocese of Szeged-Csanad, was built with public funds and will serve diocese schools and children in state care. Hungarian media coverage of the event varied, with government-tied outlets omitting the allegations against Domingo, while independent media focused on the complex's features.

Opera star Placido Domingo performed at a concert in Szeged, Hungary, to inaugurate a sports complex despite facing sexual harassment allegations. The allegations, reported by The Associated Press, span decades and involve nine women. Domingo has denied the claims, stating he believed all interactions were consensual. Hungarian media coverage of the concert varied, with government-tied outlets omitting the allegations. The sports center, funded with public money and owned by the Roman Catholic diocese, supports Bishop Laszlo Kiss-Rigo, an Orban ally. The event also featured other performers, including soprano Ana Maria Martinez and the MAV Symphony Orchestra.

Placido Domingo performed at a concert in Szeged, Hungary, to inaugurate a sports and youth complex for a local Catholic diocese, despite facing sexual harassment allegations from nine women. The allegations, reported by the Associated Press, claim Domingo used his influence to pressure women into sexual relationships. Domingo has denied the allegations, stating his interactions were consensual. The concert, which also featured his son and other performers, took place in a new sports center funded by public money and owned by the Roman Catholic diocese of Szeged-Csanad. The event highlighted the limited impact of the #MeToo movement in Hungary and the political ties of the diocese's leadership.

Opera legend Placido Domingo performed at a concert in Szeged, Hungary, to inaugurate a sports and youth complex for a local Catholic diocese, despite facing sexual harassment allegations. The allegations, reported by The Associated Press, involve nine women accusing Domingo of misconduct spanning decades. Domingo has denied the allegations, calling them inaccurate. The concert, which also featured his son and other artists, took place amid limited impact of the #MeToo movement in Hungary and political support for Prime Minister Viktor Orban's policies. The sports complex, funded by public money, will serve local schools and a soccer team.

Placido Domingo performed at the inauguration of a new soccer stadium in Szeged, Hungary, amid ongoing sexual harassment allegations. The event, attended by his son and soprano Ana Maria Martinez, received a mixed reception. While Domingo's European engagements continue, U.S. opera houses have canceled his appearances. The concert was organized by Andreas Magony, who criticized the U.S. legal culture. The new sports complex, funded by public money and church connections, will serve multiple community purposes. The article also highlights the limited impact of the #MeToo movement in Hungary and the political context surrounding the event.

The text is a comprehensive list of references related to the engineering of universal cells that can evade immune detection. It includes studies on transplantation immunology, complications of immunosuppressive therapy, and the role of MHC class I and II in immune responses. The references cover various aspects of stem cell research, including the generation of hypoimmunogenic stem cells, the role of HLA in transplantation, and the potential of induced pluripotent stem cells for therapeutic applications.