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Producer / fixer based in Seoul, South Korea
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Body mass index and self-rated health in East Asian countries: Comparison among South Korea, China, Japan, and Taiwan
The study investigates the relationship between body mass index (BMI) and self-rated health (SRH) across four East Asian countries: South Korea, China, Japan, and Taiwan. It finds that the relationship between BMI and SRH varies significantly among these countries, influenced by their unique socioeconomic and cultural contexts. In South Korea and Japan, higher BMI is associated with poorer SRH, while in China, underweight individuals report poorer SRH. Taiwan shows no significant relationship between BMI and SRH. The study highlights the importance of considering local socioeconomic and cultural factors when designing health promotion programs.
5,20-Diheterohexaphyrins: metal-template-free synthesis and aromaticity switching
The article discusses the synthesis of 5,20-Diheterohexaphyrins without the use of metal templates and explores the switching of their aromaticity. The research is published in Chem. Commun. by authors M. Umetani, J. Kim, T. Tanaka, D. Kim, and A. Osuka.
Gender differences in the impact of retirement on depressive symptoms among middle-aged and older adults: A propensity score matching approach
Retirement impacts depressive symptoms differently by gender among middle-aged and older adults in Korea. The study found that retired males exhibited higher CES-D10 scores, indicating increased depressive symptoms, while females showed no significant change. The findings suggest that retirement may be more stressful for males due to traditional gender roles and weaker social security systems in Korea. The study emphasizes the need for mental health intervention programs for retired men.
A meso–meso β‐β β‐β Triply Linked Subporphyrin Dimer
The article discusses the synthesis and characterization of a meso–meso β‐β β‐β triply linked subporphyrin dimer. The research was conducted by a team of scientists from Kyoto University and Yonsei University, focusing on the molecular structure and spectroscopic properties of the dimer.
Covalent-Frameworked 2D Crown Ether with Chemical Multifunctionality
A novel 2D crystalline framework named C2O, primarily composed of carbon and oxygen, has been synthesized and characterized. It features crown ether holes and demonstrates significant chemical stability and catalytic activity for CO2 fixation with epoxides. The C2O framework activates KI, enhancing the nucleophilicity of I– and resulting in high CO2 conversion rates. Modified versions of the framework, C2O-AGE and C2O-EEA, show even higher conversion rates, indicating the framework's potential for creating materials with diverse functionalities suitable for various applications.
Tunable Antiaromaticity by Metalation and Coordination of Lewis Acids and Aromaticity Reversal in the Triplet Excited State
Regioselectively Halogenated Expanded Porphyrinoids as Building Blocks for Constructing Porphyrin–Porphyrinoid Heterodyads with Tunable Energy Transfer
The study focuses on the synthesis of regioselective halogenated isomers of neo-confused isosmaragdyrin and their use as building blocks for constructing multichromophoric porphyrinoids. These heterodyads exhibit highly efficient energy cascade from porphyrin to isosmaragdyrin, with energy transfer processes and rates dependent on the linking sites. The research provides opportunities for developing new materials for optoelectronic applications.
Vision AI System Development for Improved Productivity in Challenging Industrial Environments: A Sustainable and Efficient Approach
The study presents a development plan for a vision AI system aimed at enhancing productivity in industrial environments with challenging environmental control. A mobile robot, SPOT, developed by Boston Dynamics, was used to obtain high-quality learning and inspection images. The proposed AI system architecture addresses challenges in applying AI technology at industrial sites, demonstrated through experimentation and application at Hyundai Motor Company's Singapore plant. The research was supported by Hyundai Motor Company and aimed to improve real-time visual inspection of manual assembly processes in automobile manufacturing.
Covalent-Frameworked 2D Crown Ether with Chemical Multifunctionality
The article details the synthesis and characterization of a novel 2D crystalline framework named C2O, composed mainly of carbon and oxygen with crown ether holes. This framework exhibits high chemical stability and significantly enhances catalytic activity for CO2 fixation with epoxides. Modified versions of C2O, such as C2O-AGE and C2O-EEA, show improved conversion rates for CO2 fixation, making the framework highly attractive for various applications due to its scalability, durability, and customizable properties.
Nonlinear Finite Element Model for Bending Analysis of Functionally-Graded Porous Circular/Annular Micro-Plates under Thermomechanical Loads Using Quasi-3D Reddy Third-Order Plate Theory
A nonlinear finite element model for axisymmetric bending of micro circular/annular plates under thermal and mechanical loading was developed using quasi-3D Reddy third-order shear deformation theory. The model accounts for material variation, porosity distributions, and geometrical nonlinearity, utilizing modified couple stress theory for strain gradient effects. The study investigates the effects of material and porosity distribution, microstructure-dependency, geometric nonlinearity, and boundary conditions on the bending response of functionally-graded porous microplates under thermomechanical loads.
Direct Numerical Simulation of Surface Wrinkling for Extraction of Thin Metal Film Material Properties
The study presents a direct numerical simulation method for extracting material properties of thin metal films based on surface wrinkling on scotch tape. This method offers a simpler and more efficient alternative to conventional finite element method (FEM)-based simulations, reducing time and complexity. The paper details the theoretical background, FEM model, and simulation results, demonstrating the method's effectiveness in determining the elastic moduli of gold and aluminum thin films. The research was supported by various Korean government ministries and the Korea Institute of Science and Technology.
Cyr61 synthesis is induced by interleukin-6 and promotes migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis
Rheumatoid arthritis (RA) is characterized by chronic inflammation leading to cartilage and bone destruction. Fibroblast-like synoviocytes (FLSs) play a crucial role in RA pathogenesis by contributing to local production of pro-inflammatory cytokines and enzymes. The study investigates the role of interleukin-6 (IL-6) in stimulating Cyr61 protein synthesis, which promotes FLS migration and invasion. Elevated IL-6 levels in RA patients enhance Cyr61 expression through the ERK/EGR3 pathway, leading to increased cell migration, invasion, and MMP2 expression. The findings suggest that targeting IL-6 downstream signaling proteins could be beneficial for RA therapy.
Associations between hand function and electrophysiological measurements in hand osteoarthritis patients of different ages with or without carpal tunnel syndrome
The study investigates the relationship between hand function and electrophysiological measurements in patients with hand osteoarthritis, with and without carpal tunnel syndrome (CTS). It highlights that CTS significantly reduces hand grip strength, pinch strength, and dexterity. The study uses nerve conduction studies (NCS) to assess these parameters and finds that electrophysiological measures, particularly those of the median motor nerve, are strong predictors of hand function. The research includes 208 patients and provides reference values for clinical functional outcome measures. The study emphasizes the importance of comprehensive rehabilitation programs that include sensory retraining and motor control to improve patients' activities of daily living and quality of life.
Three-dimensional aromaticity in an antiaromatic cyclophane
Cyclophanes are macrocyclic molecules with two aromatic subunits connected face-to-face through spacers. The study explores the synthesis, structure, and properties of AN-cyclophanes, which contain two antiaromatic π-systems. The research highlights the challenges in synthesizing AN-cyclophanes due to the instability and high reactivity of antiaromatic subunits. The study successfully synthesizes a rigid AN-cyclophane, demonstrating three-dimensional aromaticity through effective orbital interactions. The findings are supported by spectroscopic methods, theoretical calculations, and various analyses, including ring current analysis, current density analysis, and energy decomposition analysis. The study provides insights into the attractive interactions between antiaromatic systems and their potential applications in materials science.
Long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension study
A multicentre, single-arm, open-label extension study evaluated the long-term efficacy, safety, and immunogenicity of the etanercept biosimilar LBEC0101 in Korean patients with rheumatoid arthritis. The study involved patients who had completed a 52-week phase III trial and either continued with LBEC0101 or switched from the reference product to LBEC0101 for an additional 48 weeks. Results showed sustained efficacy and acceptable safety after continued therapy or switching, with no new safety concerns or increased immunogenicity. The study supports LBEC0101 as a viable alternative to the reference etanercept, with potential benefits for healthcare systems due to cost advantages.
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