Ioana Moldovan IFJ
București, Romania
Ioana Moldovan is a freelance photojournalist, documentary photographer, writer and published author based in Bucharest, Romania.
Seen in Romania Insider, Al Jazeera, Infopinia +10 more
Varicella-zoster virus infection-associated venous thromboembolism: a scoping review of 55 cases
Reporting style, Informative: Evidence-focused scoping review reporting descriptive findings and clinical conclusions, with limited interpretive language.
A scoping review of 47 publications identified 55 cases of venous thromboembolism associated with varicella-zoster virus infection. Patients were predominantly male, with an average age of 33.8 years; primary varicella was the most common infection type, and cerebral venous sinus thrombosis was the most frequent presentation. Thrombophilia testing often found temporary abnormalities, while antiviral treatment combined with antithrombotic therapy was the main approach. Most patients had a good outcome at discharge and no deaths were reported, but follow-up found sequelae in 16.2% of patients with available data, chiefly post-thrombotic syndrome. The authors emphasize early recognition and treatment while noting that longer-term complications remain relevant.
Proliferative glomerulonephritis with monoclonal IgM-kappa deposits responsive to daratumumab therapy—a case report
Reporting style, Informative: Primarily a factual clinical case report, with cautious interpretation of the potential role of daratumumab.
A 56-year-old woman with severe kidney dysfunction, fluid retention, and proteinuria had a renal biopsy indicating proliferative glomerulonephritis with monoclonal immunoglobulin deposits, including IgM-kappa deposits. After initial CyBor-D treatment, her kidney function improved enough to stop dialysis, although swelling and neuropathy persisted. Daratumumab was then given because of suspected clonal disease; it was well tolerated, and kidney function and proteinuria remained stable. The case suggests daratumumab may have a role in selected patients with suspected MGRS-related disease, while emphasizing that treatment strategies need further study.




